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Heart Palpitations Forum >> Symptoms and other concerns >> rlr I need help
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Message started by lmg83brown on Feb 5^th, 2012, 9:22am

Title: rlr I need help
Post by lmg83brown on Feb 5^th, 2012, 9:22am

Hi Rlr,

I really need your input regarding a few terms that I have learned. My doctor seems to think that ectopic's(pvc's) are caused by adrenaline's direct effect on the heart mucsle. He say's that adrenaline causes calcium ions to flood to the heart making the muscle vulnerable to ectopics. How is this different or the same to the vagus nerve induced ectopics? You say that vagus nerve ectopic's originate outside the heart, which I am trying to fully understand. But my doc also said there is a Ectopic focus needed to cause the Pvc or pac. Wouldnt that originate inside the heart. Ectopic focus are very sensative to adrenaline and im thinking that is the reason why every time I exercise or have anxiety I always experience ectopy. I think what you are saying is that all the things I mentioned(ectopic focus, calcium) are originally created by the nervous systems activity? Wouldnt large amounts of adrenaline be enough to cause ectopy on its own?(by myocardial irritation). Please explain for me, thank you so much

Title: Re: rlr I need help
Post by RLR on Feb 9^th, 2012, 6:36pm

Your doctor is referring to the bathmotropic effect, which increases a cell's responsiveness to factors that it otherwise responds to at a more basal response rate. In other words, the increase of calcium ions produces a bathmotropic effect upon the myocardial cells.

It is sometimes possible for foci to develop within the heart that respond under certain bathmotropic influence, but these foci are permanent within the heart's architecture and they do not constitute the source of benign palpitation events experienced by members and guests visiting this forum.

I've taken note of a pattern in your responses that constitute the growing approximation, but not accuracy, in the interpretation of what is considered to be the more complex areas of physiology. You appear to be heavily immersed into a realm of human science and physiology that can be quite foreboding in the absence of the prerequisite academic exposure in such a study.

While I am certainly pleased that you take greater than normal strides in seeking out relevant information on the topic, it is neither the nature nor purpose of this forum to strive for levels of dialogue that pertain more to the architecture and mechanics of human physiology than to quell the irrational fears and concerns of persons experiencing palpitations.

I take this opportunity to mention my observations because my time of late is extremely limited and I've already become quite tardy in making the more traditional responses to persons seeking inquiry. At my age, I'm simply not able to stir the same levels of endurance that were once possible in my youth and I would therefore ask that while posting of such topics is certainly welcome on the forum, I'll say in the same breath that my ability to purview and respond to this particular line of dialogue will unavoidably become far secondary to the more primary goal associated with the forum.

Thank you once again for taking such a keen interest in these matters and I trust that my responses have brought you closer to the understanding you seek.

Best regards,

Rutheford Rane, MD (ret.)